Restoration of the glycoconjugates expression in the ventral prostate of androgen-deprived mice by dihydrotestosterone: A glycohistochemical study
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چکیده
We investigated histochemically the expression of glycans in the mouse ventral prostate of the normal, castrated, castrated mice injected with testosterone (T) and castrated mice injected with dihydrotestosterone (DHT). The avidin-biotinperoxidase complex technique was used with eight biotinylated lectins, on paraffin sections. Remarkably, contrarily to T, the DHT found to restore all the glycans in epithelial cells of ventral prostate. The histophysiological significance of the activation synthesis of glycoconjugates in mouse ventral prostate by DHT is discussed in the light of the other studies obtained mainly in humans.
منابع مشابه
Androgen status and expression of glycoconjugates and lectins in the epithelial cells of the mouse ventral prostate. A glycohistochemical approach.
We investigated histochemically the expression of glycans and endogenous sugar-binding proteins (endolectins) in the ventral prostate of normal and androgen-deprived mice. The avidin-biotin-peroxidase complex technique was used with a panel of biotinylated lectins and neoglycoproteins, respectively, on paraffin sections. Characteristic binding patterns depending upon the type of lectin were obs...
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تاریخ انتشار 2016